I work on Mac and on Linux. I used to use macports for python (sorry, I'm opinionated, I won't touch brew), along with either venv or virtualenv. But I've found

I work on Mac and on Linux. I used to use macports for python (sorry, I'm opinionated, I won't touch brew), along with either venv or virtualenv. But I've found that working within the Anaconda system for python has been the best experience overall. I've found conda environments to be a pretty clean solution.