3 ms·
Adding to some of the other comments: Leukocytes (immune cells) such as B and T cells will undergo "education" when they are developing. For example, B cells, b
by abbirdboy 7y ago
Adding to some of the other comments: Leukocytes (immune cells) such as B and T cells will undergo "education" when they are developing. For example, B cells, before being released, will go through something called central tolerance in the bone marrow. If the B cell receptors bind a "self" antigen (markers that are associated with our own cells) while developing, it will go through negative selection and be destroyed. Of course, some B cells that bind self antigens do make it through in rare cases and this is what manifests as an autoimmune disease.
- airstrike 7y agoThanks for this. I'm perpetually amazed at how mind-bogglingly complex the human body is. > while developing, it will go through negative selection and be destroyed Can you share more about how this process works? Even just a link would do. Thank you!
- Footkerchief 7y agohttps://en.wikipedia.org/wiki/V(D)J_recombination https://en.wikipedia.org/wiki/V(D)J_recombination
- abbirdboy 7y agoI think Khan Academy does a good job of explaining it: https://www.youtube.com/watch?v=EsQyCHs4IBY https://www.youtube.com/watch?v=EsQyCHs4IBY
- deleted 7y ago[deleted]