I've recently started using a tablet/pen, and for most purposes it's a good mouse replacement, and it's also better for sketching. Using buttons on the pen is

I've recently started using a tablet/pen, and for most purposes it's a good mouse replacement, and it's also better for sketching. Using buttons on the pen is a bit fiddly, but tapping the pen is an equivalent in most situations. For playing traditional kinds of PC games I notice that the mouse is still by far the best option though.