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Yep -- OxyContin has a timed-release coating and by preventing the "peaks and valleys" of opiate use, it was supposed to minimize addiction. This was a major se
by l_t 7y ago
Yep -- OxyContin has a timed-release coating and by preventing the "peaks and valleys" of opiate use, it was supposed to minimize addiction. This was a major selling point for doctors, which turned out be based on falsified data.
The thing is, I don't think any studies have actually validated that concept? If you say "it's basically known", I'm curious what evidence you have for that statement. Are there studies where people have been prescribed more opioids but been less addicted because they finally have "sufficient" medication?
- tempestn 7y agoI didn't say, "It's basically known." I said, "Isn't it basically known?" I'm just going from memory, probably of news articles. I would be interesting to know what follow-up research has been done as well.
- l_t 7y agoAh, my bad. I thought that was meant to be a rhetorical question.
- tempestn 7y agoNo, I could have been more clear for sure. I can see how you read it that way. Also fwiw my reply should have been "I would be interested to know," not "I would be interesting." Although maybe I would be more interesting too, if I could supply that information...
- adamsb6 7y agoAnecdotal from a history of more than a few surgeries: I think the OxyContin is actually less addictive. A pain relieving dose of a non time release opioid will last about four hours. I’ve had pain bad enough that it prevents sleep. To get a good eight hours of sleep I would need to take a much higher dose, and that puts you pretty deep into euphoria. Some people will keep chasing that feeling. With OxyContin I could take a normal dose before bed and sleep through the night.