2 ms·
Do this again, but this time with a better selection of genes? The outcome isn't a refutation of the approach, only of the particular gene drive. No reason why
by yyyk 7y ago
Do this again, but this time with a better selection of genes? The outcome isn't a refutation of the approach, only of the particular gene drive. No reason why we can't do better next time.
- ianai 7y agoI hope they see it your way. They apparently used males from another species of mosquito. The females selectively chose against them. They should use the local species in another trial.
- Nasrudith 7y agoI think the main thing it pointed out was to locally source the specimens to avoid any accidental hybrid vigor if they managed to mutate out to something viable. Of course the outcome as is proves that males seem to make a poor long term solution since healthy ones can one to many enough to largely recover. It could theoretically weaken their genepool into nonviability if done persistently enough that the only mutant defective and inbred will survive but that would probably take a long time to converge to extinction.
- ianai 7y agoSelf limiting is needed.