2 ms·
> You can't ensure delivery or uniform uptake otherwise That's all true (and I agree), but that's a practical/technical issue. That may be solvable, but even i
by mbreese 7y ago
> You can't ensure delivery or uniform uptake otherwise
That's all true (and I agree), but that's a practical/technical issue. That may be solvable, but even in that case, that's not the whole story. There are also developmental biology issues at play once you have a full organism (or even an embryo that is just a few cell divisions in). The way our bodies operate as adults is just as much a function of how our cells developed and grew as it is a product of genetics. There are a lot of processes that happen only at very specific timepoints in development. And once you're past those points, editing the genes required won't have any phenotypic effect.
We can alter genetics with CRISPR. We can't alter morphology in the same way. For example, in certain eye diseases, you can have a loss of a gene that is involved in how the retina processes light. But, the same gene is also involved in how the optic nerve is formed (or migrates) in the brain. You could use gene editing approaches to knock in a good copy of the gene, which might help the retina absorb light, but the nerves have already formed and are already in place. That isn't going to change.
And none of that actually addresses the ethics involved in changing the genetics of a person, which is non-trivial to say the least.