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Thanks for the excellent and detailed reply! Are there any papers you recommend im particular? One of the harder parts of getting into a new domain of science i
by gradys 7y ago
Thanks for the excellent and detailed reply! Are there any papers you recommend im particular? One of the harder parts of getting into a new domain of science is that it's hard to tell the good/important papers from the others.
- aaavl2821 7y agoI'm not the best person to answer this, as I generally just read the stuff my friends send me, but here is the original CRISPR paper: https://science.sciencemag.org/content/337/6096/816 https://science.sciencemag.org/content/337/6096/816 May also be interesting to read this paper on a gene editing tech, which ending up being irreproducible. original paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077703/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077703/ biorxiv manuscript showing science isnt reproducible: https://www.biorxiv.org/content/10.1101/704197v1 https://www.biorxiv.org/content/10.1101/704197v1 article summarizing the above papers: https://blogs.sciencemag.org/pipeline/archives/2019/07/26/virus-only-gene-editing-or-not https://blogs.sciencemag.org/pipeline/archives/2019/07/26/vi... Other labs that off the top of my head that are active in gene editing are Feng Zhang, David Liu, Matthew Porteus. Of course I am missing most of the important labs but these are some important players