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THC (Tetrahydrocannabinol) activates cannabinol receptors in one's brain whenever they smoke cannabis. These receptors are responsible to stimulating hunger (wh

THC (Tetrahydrocannabinol) activates cannabinol receptors in one's brain whenever they smoke cannabis. These receptors are responsible to stimulating hunger (why you get munchies) but they also stimulate something called long term depression, which is the process by which your brain forgets memories. The effects take years to decades for anything significant enough to precipitate. Now, I'm not against smoking cannabis just like I'm not against drinking alcohol. I'm for people understanding the risk factors and being fully informed before they make a decision.

rewgs 7y ago
> The effects take years to decades for anything significant enough to precipitate. This sentence is weird to me. Can you rephrase?
- craftyguy 7y ago
  They are trying to say that THC can cause depression, but it can take many years. I'm just clarifying (and not downvoting, like the rest of 'hacker' 'news'.. lol) and do not necessarily agree/disagree with OP
  - will123195 7y ago
    long-term "depression" (LTD) is an activity-dependent reduction in the efficacy of neuronal synapses
  - deelowe 7y ago
    That doesn't sound like what they were trying to say.
    - craftyguy 7y ago
      .. then please do elaborate/explain away.... FFS your comment is not at all helpful.
      - deelowe 7y ago
        The OP added more context to their comment. Maybe go re-read? This has nothing to do with clinical depression.
MiroF 7y ago
Source? I would love to be fully informed but I don't think the science is nearly as settled as you are making it out to be
- Medicalidiot 7y ago
  I was going off my undergraduate neuroscience course when I asked my professor who has his doctorate in neurophysiology about long term cannabis use. Looking at Wikipedia (https://en.wikipedia.org/wiki/Long-term_effects_of_cannabis#Memory_and_intelligence https://en.wikipedia.org/wiki/Long-term_effects_of_cannabis#...) you're right that it's fairly inconclusive and there may be some cofounding variables at play which are preventing us from assigning a firm sequela. Active cannabis users will have memory deficits.

rewgs 7y ago

> The effects take years to decades for anything significant enough to precipitate. This sentence is weird to me. Can you rephrase?

craftyguy 7y ago
They are trying to say that THC can cause depression, but it can take many years. I'm just clarifying (and not downvoting, like the rest of 'hacker' 'news'.. lol) and do not necessarily agree/disagree with OP
- will123195 7y ago
  long-term "depression" (LTD) is an activity-dependent reduction in the efficacy of neuronal synapses
- deelowe 7y ago
  That doesn't sound like what they were trying to say.
  - craftyguy 7y ago
    .. then please do elaborate/explain away.... FFS your comment is not at all helpful.
    - deelowe 7y ago
      The OP added more context to their comment. Maybe go re-read? This has nothing to do with clinical depression.

MiroF 7y ago

Source? I would love to be fully informed but I don't think the science is nearly as settled as you are making it out to be

Medicalidiot 7y ago
I was going off my undergraduate neuroscience course when I asked my professor who has his doctorate in neurophysiology about long term cannabis use. Looking at Wikipedia (https://en.wikipedia.org/wiki/Long-term_effects_of_cannabis#Memory_and_intelligence https://en.wikipedia.org/wiki/Long-term_effects_of_cannabis#...) you're right that it's fairly inconclusive and there may be some cofounding variables at play which are preventing us from assigning a firm sequela. Active cannabis users will have memory deficits.