3 ms·
> This may be what more studies in the future will look like: Bundle multiple interventions together to help create statistically stronger results, at the cost
by vanderZwan 7y ago
> This may be what more studies in the future will look like: Bundle multiple interventions together to help create statistically stronger results, at the cost of less clarity around each individual treatment
I'm probably stating the obvious, but it may also be that multiple interventions together have a larger net effect than the interventions separately would suggest. I recently read an article by a physician arguing for many of his patients, treating ADHD with a combination of a stimulant and a non-stimulant resulted in bigger benefits with less side-effects, due to being able to have a lower dosage for each individual medication[0].
[0] https://www.additudemag.com/adhd-medication-combination-therapy-treatment/ https://www.additudemag.com/adhd-medication-combination-ther...
- drcode 7y agoI agree that synergy is an important element, but to me a study like this could make sense even without synergy: To me, it seems better to have 4x the statistical data on 4 drugs at once than just running the individual studies, given how long a study like this takes.