4 ms·

Title should be changed to something like the interpretation section: "Dairy consumption was associated with lower risk of mortality and major cardiovascular di

Title should be changed to something like the interpretation section: "Dairy consumption was associated with lower risk of mortality and major cardiovascular disease events in a diverse multinational cohort." The study does not, and does not purport to, show a causal relationship. EDIT: It appears that the title here has been changed, but to the article title, which is a bit less than ideal since it implies a positive correlation when the study shows a negative correlation (or at least it reads that way to me).

bookofjoe 7y ago
Concur.
dcolkitt 7y ago
The condition "diverse multinational cohort" is very important. The primary driver of population level variance in dairy consumption is lactose tolerance. For example Northern Europeans have much higher lactose tolerance than Aboriginal Australians. So, we have to be really careful that dairy consumption isn't just proxying for ancestry. Because there are huge genetic variations in CVD mortality across different sub-populations. For example African-Americans have signficantly higher CVD, BP and diabetes risk because of higher rates of APOL1 polymorphism. [1]https://jasn.asnjournals.org/content/26/2/247 https://jasn.asnjournals.org/content/26/2/247
- nostromo 7y ago
  I suspect lactose intolerance in the US is inversely correlated with wealth -- so this could just be another study showing that wealthy folks live longer.
  - mac01021 7y ago
    > actose intolerance in the US is inversely correlated with wealth I'm not well informed about the causes of lactose intolerance. Is this correlation diet-induced/environmental? Or is it a congenital/racial thing where white people be rich and everyone else is genetically intolerant?
    - shafyy 7y ago
      The latter.
    - mr_toad 7y ago
      Lactose intolerance is the norm. Tolerance is unusual in adult mammals. In humans, it appears to be a very recent mutation, probably associated with the domestication of livestock. https://en.wikipedia.org/wiki/Lactase_persistence https://en.wikipedia.org/wiki/Lactase_persistence
Zenst 7y ago
Does this mean that lack of dairy consumption is associated with a higher risk? Maybe, maybe not. I'd love to see some data that included a large group of people who are lactose-intolerant. But whatever you read, the biggest threat to your health in many ways, will always be stress. So don't panic and remember, quality over quantity every time.
didibus 7y ago
Hum, your comment also confuses me. But the study to me seem to say that Dairy consumption is good for you, and lowers the risks of death or cardiac disease. So keep drinking that milk folks!

bookofjoe 7y ago

Concur.

dcolkitt 7y ago

The condition "diverse multinational cohort" is very important. The primary driver of population level variance in dairy consumption is lactose tolerance. For example Northern Europeans have much higher lactose tolerance than Aboriginal Australians. So, we have to be really careful that dairy consumption isn't just proxying for ancestry. Because there are huge genetic variations in CVD mortality across different sub-populations. For example African-Americans have signficantly higher CVD, BP and diabetes risk because of higher rates of APOL1 polymorphism. [1]https://jasn.asnjournals.org/content/26/2/247 https://jasn.asnjournals.org/content/26/2/247

nostromo 7y ago
I suspect lactose intolerance in the US is inversely correlated with wealth -- so this could just be another study showing that wealthy folks live longer.
- mac01021 7y ago
  > actose intolerance in the US is inversely correlated with wealth I'm not well informed about the causes of lactose intolerance. Is this correlation diet-induced/environmental? Or is it a congenital/racial thing where white people be rich and everyone else is genetically intolerant?
  - shafyy 7y ago
    The latter.
  - mr_toad 7y ago
    Lactose intolerance is the norm. Tolerance is unusual in adult mammals. In humans, it appears to be a very recent mutation, probably associated with the domestication of livestock. https://en.wikipedia.org/wiki/Lactase_persistence https://en.wikipedia.org/wiki/Lactase_persistence

Zenst 7y ago

Does this mean that lack of dairy consumption is associated with a higher risk? Maybe, maybe not. I'd love to see some data that included a large group of people who are lactose-intolerant. But whatever you read, the biggest threat to your health in many ways, will always be stress. So don't panic and remember, quality over quantity every time.

didibus 7y ago

Hum, your comment also confuses me. But the study to me seem to say that Dairy consumption is good for you, and lowers the risks of death or cardiac disease. So keep drinking that milk folks!