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I did admit to being a little pedantic. But upon reflection, it's arguable that the paper would have been more interesting if they had included L-canavanine, i
by mirimir 7y ago
I did admit to being a little pedantic.
But upon reflection, it's arguable that the paper would have been more interesting if they had included L-canavanine, in addition to L-arginine and three analogs with shorter cationic side chains. Because we know that it can be incorporated during protein synthesis, in place of L-arginine. But none of their analogs can.
So if L-canavanine had been incorporated into peptides in their tests, more or less as well as L-arginine, that would arguably have ruled out their hypothesis.
- dmix 7y agoI'll defer to you on that, you seem more informed on the subject than me. Makes me want to revisit my biology reading list.