Horrible title as some point out. I got a good tl;dr from the first paper related to the article (same authors): "Comprehensive population models, such as the

Horrible title as some point out. I got a good tl;dr from the first paper related to the article (same authors): "Comprehensive population models, such as the one we have presented here, seek to link cellular properties and network structure to dynamics and function, the ultimate goal being to use these models to test hypotheses and to suggest future experiments. We propose that for areas of the brain about which there are sufficient data, such as the visual cortex, it is time to move to next-generation models that are more comprehensive, data driven, and dynamic. Such a move would constitute a paradigm shift in computational neuroscience, and the present model is a step in that direction." Basically they want more than just a simplified mathematical model, something that accounts for all the measured data. I'm not sure this is the right approach, and only some example application would show if it is. I don't think they applied their model yet or whether it can be applied, just browsed the first paper.