We know about lots of things that math doesn't explain. AFAICT there are reasonable information-theoretic grounds for suspecting that many if not most things we

We know about lots of things that math doesn't explain. AFAICT there are reasonable information-theoretic grounds for suspecting that many if not most things we might want to ask about won't yield the the kind of explanations we find satisfying. Irreducible complexity is a thing, at least apparently, and among documented phenomena there is a spectrum of amenability to formal modelling. Statements expositing an 'unreasonable effectiveness of mathematics' or TFA's aesthetic rendition don't seem to amount to more than 'some phenomena admit simple explanations'. Much more often the best effective mathematical explanation is a lukewarm admixture of awkward cludges, or is simply non-existent.