Don’t know what your hardware is, but there are libraries that can do some computations in parallel. You’ll want to look into using a parallel backend in R. It

Don’t know what your hardware is, but there are libraries that can do some computations in parallel. You’ll want to look into using a parallel backend in R. It will depend on the system architecture. As for libraries that may help potentially, speedglm, biglm, There’s also some options from bioconductor: https://bioconductor.org/packages/release/data/experiment/vignettes/RegParallel/inst/doc/RegParallel.html https://bioconductor.org/packages/release/data/experiment/vi... You could also try glmnet with a parallel backend.