I hypothesize there very well could also be differences between "morning people" and "evening/night people". The dosing guides that suggest taking before/after

I hypothesize there very well could also be differences between "morning people" and "evening/night people". The dosing guides that suggest taking before/after meals could be more specific (E.G. your primary meal), while dosing patterns for regular drugs might be completely different and even benefit from some patients taking stronger/weaker doses (at different times of the day) based on how their body is reacting. All of this would be much easier with, and the correct contribution of tech would be, integrated continuous telemetry from smart sensors and systems. That data would also be a privacy nightmare and should be something that the patient can read and choose to share or not.