Yes, although it's not entirely straightforward and there are many sharp edges, so it's maybe not for the faint of heart. Since I just did it, here's a guide I

Yes, although it's not entirely straightforward and there are many sharp edges, so it's maybe not for the faint of heart. Since I just did it, here's a guide I wrote up with my specific hardware and some of the issues I've encountered to set up my system specifically for VR passthrough: https://forum.level1techs.com/t/zen2-ryzen-3700x-and-x570-asus-c8h-win-10-vr-on-arch-linux/146080 https://forum.level1techs.com/t/zen2-ryzen-3700x-and-x570-as... Note: I haven't dealt with sound yet, which is another potential sticking point if you're doing gaming (most people seem to use a separate sound device, although I've seen some people use network sound when running into issues; HDMI sound I assume would work fine if you're doing GPU pass through) since I was just focused on getting my VR HMD working, which has it's own sound output already. IOMMU groups are defined by AGESA and the X570 boards in general seem to have much finer grained groupings vs earlier AMD chips/boards (although people seem to have done ACS workarounds). My recommendation is to find something that someone has gotten working already and just follow along (the VFIO subgroup at level1techs and r/VFIO on reddit seem to be the best resources).