3 ms·

It seems strange to say that "scientific consensus is that these fears are unsubstantiated" (i.e. it's okay to inject Thiomersal into the body), when in the sam

by calebm 7y ago

It seems strange to say that "scientific consensus is that these fears are unsubstantiated" (i.e. it's okay to inject Thiomersal into the body), when in the same wikipedia article, it says: "Thiomersal is very toxic by inhalation, ingestion, and in contact with skin (EC hazard symbol T+), with a danger of cumulative effects." Anyone else's BS detector going off over this?

rolph 7y ago
yes exactly, now there is the thing about how wikipedia is set up for editing. these articles have a process for editorilizations, or corrections, but i havnt gotten into it too far. there is a problem with ethyl mercury toxicity being compared to METHYL mercury toxicity, which is extremely toxic. This creates modulation effect as in oh its only ethyl mercury. heres a paragraph from this link: https://en.wikipedia.org/wiki/Ethylmercury https://en.wikipedia.org/wiki/Ethylmercury The toxicity of ethylmercury, for instance as it derives in vivo from thimerosal, is not well studied, and for many years, studies of methylmercury were used as a basis to predict the safety and estimate the risk of thimerosal use.[citation needed] Methylmercury and ethylmercury distribute to all body tissues, crossing the blood–brain barrier and the placental barrier, and ethylmercury also moves freely throughout the body.[3] Risk assessment for effects on the human nervous system have been made by extrapolating from dose-response relationships for methylmercury.[4] Clifton has offered the estimate that ethylmercury clears from blood with a half-life of seven to 10 days in adult humans.[5] However, preliminary direct evidence from a 2005 animal study, subsequently summarised in an NIAID fact sheet on the use of thimerosal, suggested that methylmercury is an inadequate reference compound for evaluating the toxicology of ethylmercury, because the two compounds differ significantly in the ratio of organic to inorganic mercury each produces in the brain, as well as in their individual tissue distributions and clearance rates.[6][7][8][9] Taken together, the researchers conclude from their monkey study of ADME for inoculated thimerosal-derived ethylmercury and the stomach-administered methylmercury that past and ongoing studies of methylmercury are unsuitable as a basis for evaluating thimerosal toxicity, and that thimerosal risk assessment "based on blood mercury measurements may not be valid" [emphasis added].[10]

by calebm 7y ago

rolph 7y ago

yes exactly, now there is the thing about how wikipedia is set up for editing. these articles have a process for editorilizations, or corrections, but i havnt gotten into it too far. there is a problem with ethyl mercury toxicity being compared to METHYL mercury toxicity, which is extremely toxic. This creates modulation effect as in oh its only ethyl mercury. heres a paragraph from this link: https://en.wikipedia.org/wiki/Ethylmercury https://en.wikipedia.org/wiki/Ethylmercury The toxicity of ethylmercury, for instance as it derives in vivo from thimerosal, is not well studied, and for many years, studies of methylmercury were used as a basis to predict the safety and estimate the risk of thimerosal use.[citation needed] Methylmercury and ethylmercury distribute to all body tissues, crossing the blood–brain barrier and the placental barrier, and ethylmercury also moves freely throughout the body.[3] Risk assessment for effects on the human nervous system have been made by extrapolating from dose-response relationships for methylmercury.[4] Clifton has offered the estimate that ethylmercury clears from blood with a half-life of seven to 10 days in adult humans.[5] However, preliminary direct evidence from a 2005 animal study, subsequently summarised in an NIAID fact sheet on the use of thimerosal, suggested that methylmercury is an inadequate reference compound for evaluating the toxicology of ethylmercury, because the two compounds differ significantly in the ratio of organic to inorganic mercury each produces in the brain, as well as in their individual tissue distributions and clearance rates.[6][7][8][9] Taken together, the researchers conclude from their monkey study of ADME for inoculated thimerosal-derived ethylmercury and the stomach-administered methylmercury that past and ongoing studies of methylmercury are unsuitable as a basis for evaluating thimerosal toxicity, and that thimerosal risk assessment "based on blood mercury measurements may not be valid" [emphasis added].[10]