I agree that prohibition does cause a lot of issues. This makes even less sense since one difference is that there is no equivalent to "alcohol poisoning" with

I agree that prohibition does cause a lot of issues. This makes even less sense since one difference is that there is no equivalent to "alcohol poisoning" with LSD. A dose at which LSD is physically toxic is so high (200 times a recreational dose) that it's incredibly unlikely to take by accident. As far as I know, there are no known overdose deaths due to LSD. (However, there are analogues to LSD that are toxic: 25I-NBOMe and 25C-NBOMe).