36 ms·
> thermal model of a brain No, it doesn't predict activity from parameters. > C. elegans, and even that's debatable because it does not model chemical process
by marmaduke 7y ago
> thermal model of a brain
No, it doesn't predict activity from parameters.
> C. elegans, and even that's debatable because it does not model chemical processes
"the map is not the territory". This sort of criticism isn't even scientific
- dTal 7y agoA thermal model sure does predict brain activity from parameters. I can say with high confidence that the brain will have very little activity at 0 degrees C.
- marmaduke 7y agoThat's a narrow range of identifiability with no relevance to the data we collect on a daily basis or the scientific questions being asked (beyond of course that it is a pedantic example)
- p1esk 7y agothe map is not the territory Not sure what you mean.
- marmaduke 7y agohttps://en.m.wikipedia.org/wiki/Map%E2%80%93territory_relation#%22A_map_is_not_the_territory%22 https://en.m.wikipedia.org/wiki/Map%E2%80%93territory_relati... For example, we have a whole brain model of rest state dynamics that can represent aspects of data (eg graph metrics such as degree) from multiple sclerosis patients, distinctly from healthy controls. Here, the map is the model parameters, and the territory is the patient's actual brain. The map is deemed useful if its structure represents that of the territory.
- p1esk 7y agoWhether you like it or not, when you say "whole brain simulation" most people will interpret it as a fully functioning model of an entire human brain [1]. If you mean something other than that, you should be more specific (e.g. "a whole brain model of rest state dynamics"). [1] https://en.wikipedia.org/wiki/Brain_simulation https://en.wikipedia.org/wiki/Brain_simulation
- marmaduke 7y agoI don't have an opinion on the subject, but this is what we call it in this domain (and HBP, the subject of the original article)