4 ms·

Would the molecules cross the blood brain barrier? Is there a trial of this anywhere? (I have an inoperable brain tumor.)

• JBReefer 7y ago
  What’s that like? I’m sorry that happened to you.
  • chrisbennet 7y ago
    I’m happy and haven’t had to buy lunch in the last couple of months. :-) I’ve still got a year or so till it kills me. It is difficult on my wife, family and friends.
• izuchukwu 7y ago
  I’m not a doctor, this is very much not medical advice, and I’ve only been looking into these recently, but it does appear that the Benzimidazole class of medications from that recent cured-by-dog-dewormer post [0] like Albendazole and Mebendazole, both FDA approved as antihelmintics, do pass through the blood-brain barrier [1][2], and is currently used to that effect as a standard treatment for neurocysticercosis. It appears a neurosurgery professor at Johns Hopkins that independently discovered the link was interested in it for that very reason [3]. [0]: https://news.ycombinator.com/item?id=20486893 https://news.ycombinator.com/item?id=20486893 [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874411/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874411/ [2]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403762/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403762/ [3]: https://www.npr.org/sections/health-shots/2017/01/30/512400204/a-pinworm-medication-is-being-tested-as-a-potential-anti-cancer-drug https://www.npr.org/sections/health-shots/2017/01/30/5124002...
  • chrisbennet 7y ago
    Thank you.