Rephrasing it as "fundamentally impractical with Silicon transistor-based computers" might make the statement quite a bit easier to defend without substantially

Rephrasing it as "fundamentally impractical with Silicon transistor-based computers" might make the statement quite a bit easier to defend without substantially changing the meaning. There's no magic in the human brain, but we're nowhere near capable of building one in the lab and certainly not simulating one in a computer. We're so far away from doing either of those things, that we really have no frame of reference to even talk about whether AGI is possible or practical.