Im glad that epigenetics is being discussed, but I'm a but confused by this article. Not sure what this has to do with the central dogma, and last I heard the r

Im glad that epigenetics is being discussed, but I'm a but confused by this article. Not sure what this has to do with the central dogma, and last I heard the role of TADs is still not properly understood. There was also some talk about studies showing the number of differences on average from the human genome, and how that worked played a role in developing epigenetic drugs - but the differences int he genome are genetic, not epigenetic. And DNA methylation/histone acetylation are all probably involved with 3D structure, but the development of epigenetic drugs isn't really focused on 3d genome modification AFAIK, since it's still very poorly understood. Overall, I'm a bit confused by the point the article is trying to make - it seems like the author is cutting and pasting things from different sources without understanding the fundamentals behind it leading to a lot of confusing/irrelevant/wrong statements- but maybe I'm missing something. I do appreciate that there is interest in epigenetics- it's a fascinating and important field.