> Anyway, this paper shows that a cell population can have a bimodal phenotypic distribution without cooperativity, > simply by having single proteins that res

> Anyway, this paper shows that a cell population can have a bimodal phenotypic distribution without cooperativity, > simply by having single proteins that respond in non-linear fashion to their environment. That's...a new statistical law? What I mean by a "new law" is the formula that describes the conditions for bimodality [of the output distribution resulting from a gamma-distributed input passing a nonlinear filter in the form 1/(1+x)^n or 1/(1+x^n)] in terms of the intersection of two curves (those curves have a well-defined experimental meaning). Maybe, as one of the internauts remarked, this should rather read "a new law based on statistical theory". The language used in the press release was simplified (perhaps over-simplified).