I manage to do pretty well. A good uninstaller (which performs deep scans), a defragmenter (MyDefrag is best) and CCleaner will do the trick. But it's true tha

I manage to do pretty well. A good uninstaller (which performs deep scans), a defragmenter (MyDefrag is best) and CCleaner will do the trick. But it's true that a little reinstall once every few years can't give a slight speedup. Nowadays I tend toward a nomad setup (using portable apps) anyway, so it's even easier.