4 ms·

Seems like it has never been tested in humans. Lets hold the hype train for now. Promising drugs like this a dime a dozen. Proving that they work from this sta

Seems like it has never been tested in humans. Lets hold the hype train for now. Promising drugs like this a dime a dozen. Proving that they work from this stage is the hard part. This is what big pharma specializes in.

rolleiflex 7y ago
Antibiotics don’t work on humans. They work on bacteria in humans. Your sentiment is generally correct for most other types of medical research, but antibiotics generally pass the human testing fairly easily, provided that they don’t also kill the human they’re tested on.
- PunksATawnyFill 7y ago
  Which gives us products like Cipro and the other quinolones, which destroy tendons. It only took 20 years and how many degraded lives and ended careers before the FDA issued a warning: https://www.webmd.com/osteoarthritis/news/20080708/fda-warning-cipro-may-rupture-tendons https://www.webmd.com/osteoarthritis/news/20080708/fda-warni... Obviously antibiotics save lives, but let's hope the next generation is used judiciously. There are doctors out there prescribing Cipro as the first line of defense for trivial infections, and there's no excuse for it.
- maxerickson 7y ago
  Don't be so tiresome. They obviously mean that they hope that the drugs don't kill or excessively harm the human. Antibiotics that kill cilia or kidneys or livers are doing something or other to humans, in addition to working on microorganisms.
refurb 7y ago
I had the exact same thought. The R&D landscape is littered with antibiotics that kill bacteria but can’t be used in humans.
- TeMPOraL 7y ago
  Couldn't these be still used as sanitation agents?
  - tempguy9999 7y ago
    Oh hell no! AFAIK, though I'm no expert, resistance to antibiotic x may give partial resistance to antibiotic y. Or worse "Resistance to triclosan [not an antibiotic] could lead to resistance to other biocides or antibiotics." https://ec.europa.eu/health/scientific_committees/opinions_layman/triclosan/en/index.htm https://ec.europa.eu/health/scientific_committees/opinions_l... Indeed I think this may have been confirmed now. Heat and/or simple chemicals have to be a better option. Edit: that study cited is outdated, this is more current and less 'maybe': https://www.sciencedirect.com/science/article/pii/S0160412018303672 https://www.sciencedirect.com/science/article/pii/S016041201... is more recent.

rolleiflex 7y ago

Antibiotics don’t work on humans. They work on bacteria in humans. Your sentiment is generally correct for most other types of medical research, but antibiotics generally pass the human testing fairly easily, provided that they don’t also kill the human they’re tested on.

PunksATawnyFill 7y ago
Which gives us products like Cipro and the other quinolones, which destroy tendons. It only took 20 years and how many degraded lives and ended careers before the FDA issued a warning: https://www.webmd.com/osteoarthritis/news/20080708/fda-warning-cipro-may-rupture-tendons https://www.webmd.com/osteoarthritis/news/20080708/fda-warni... Obviously antibiotics save lives, but let's hope the next generation is used judiciously. There are doctors out there prescribing Cipro as the first line of defense for trivial infections, and there's no excuse for it.
maxerickson 7y ago
Don't be so tiresome. They obviously mean that they hope that the drugs don't kill or excessively harm the human. Antibiotics that kill cilia or kidneys or livers are doing something or other to humans, in addition to working on microorganisms.

refurb 7y ago

I had the exact same thought. The R&D landscape is littered with antibiotics that kill bacteria but can’t be used in humans.

TeMPOraL 7y ago
Couldn't these be still used as sanitation agents?
- tempguy9999 7y ago
  Oh hell no! AFAIK, though I'm no expert, resistance to antibiotic x may give partial resistance to antibiotic y. Or worse "Resistance to triclosan [not an antibiotic] could lead to resistance to other biocides or antibiotics." https://ec.europa.eu/health/scientific_committees/opinions_layman/triclosan/en/index.htm https://ec.europa.eu/health/scientific_committees/opinions_l... Indeed I think this may have been confirmed now. Heat and/or simple chemicals have to be a better option. Edit: that study cited is outdated, this is more current and less 'maybe': https://www.sciencedirect.com/science/article/pii/S0160412018303672 https://www.sciencedirect.com/science/article/pii/S016041201... is more recent.