The imaging depth that I was aware of at the time (um) would have allowed imaging with the DNA is solution... so ostensibly introns and other physical attribute

The imaging depth that I was aware of at the time (um) would have allowed imaging with the DNA is solution... so ostensibly introns and other physical attributes could have been imaged. Also 20 years ago we didn't have good automated shotgun techniques so everyone was trying to solve that problem.