It doesn't take particularly long to sequence a human genome. If you want long reads, you need to spend more time sitting on the machine. Last I checked, the li

It doesn't take particularly long to sequence a human genome. If you want long reads, you need to spend more time sitting on the machine. Last I checked, the limiting steps were contention for machine time and library prep. If you're doing a custom library prep it can be very time consuming, but I believe the trend is moving toward whole exome sequencing. We should see sub-$5k exomes (at scale) in 2011.