If you spend 300$ million in secret research you can realize 1.5 billion in profit. The numbers for research where you're forced to make the production researc

If you spend 300$ million in secret research you can realize 1.5 billion in profit. The numbers for research where you're forced to make the production research public mean your competitors can get to market faster and it may mean an investment of even 3 million isn't worth it. There are some medicines/procedures/devices where this is the only way to make the numbers work to sell it.