GLPK really came through for me once. I was working with some academic code that had been written in Python. The Python was writing AMPL scripts and then invo

GLPK really came through for me once. I was working with some academic code that had been written in Python. The Python was writing AMPL scripts and then invoking a commercial solver on them. I bound to GLPK using CFFI and replaced all of the AMPL with direct calls into the library. The performance improvement was about 4 orders of magnitude.