With Smalltalk? Sure. With Seaside? No, that's not what it was designed for. I haven't yet convinced Twitter to do a rewrite in Smalltalk ;). But it would be a

With Smalltalk? Sure. With Seaside? No, that's not what it was designed for. I haven't yet convinced Twitter to do a rewrite in Smalltalk ;). But it would be a step up from Ruby, even if only to get a better garbage collector.