You cannot assume a null result without testing against it rigorously. Gwern level of tests are way not rigorous nor sensitive enough. Which is why this is muc

You cannot assume a null result without testing against it rigorously. Gwern level of tests are way not rigorous nor sensitive enough. Which is why this is much more useful. Blinding is relatively easy with substances that are active at very low doses and have relatively unpredictable effects.