For any chemists out there - the tl;dr is that the chemists worked out how to break C-H bonds and replace them with a radioactively labeled C-18F bond for on ar

For any chemists out there - the tl;dr is that the chemists worked out how to break C-H bonds and replace them with a radioactively labeled C-18F bond for on aromatic rings which is pretty cool. The molecule can then be traced through the body using PET It'll be interesting to know how labelling of F would affect the chemistry of a compound - F is a fairly nice choice given that it is quite small so shouldn't introduce much steric difference. That said, F far more electronegative than H which could affect some degree of solubility and possibly the reactive site if it is closely situated.