MySQL will have to be run on the instance itself, not on S3. Just pretend it's a normal computer, except that you have to have a plan for backups from the very

MySQL will have to be run on the instance itself, not on S3. Just pretend it's a normal computer, except that you have to have a plan for backups from the very beginning. I recommend the book "High Performance MySQL" from O'Reilly. It's helped me out a lot witih how to manage MySQL. Has chapters on backups/replication/high availability.