Just finished reading the paper, particularly interested in the mitochondrial biogenesis part. They make several comparisons with exercise adaptations, and the

Just finished reading the paper, particularly interested in the mitochondrial biogenesis part. They make several comparisons with exercise adaptations, and the authors conclude: >>> The present study reveals that UA induces a molecular signature response, in both the plasma and skeletal muscle of humans, resembling that observed as a consequence of a regular exercise regimen. The also selected sedentary people only (from their participant inclusion criteria). Note that this is somehow normal: I have been rejected twice in 2 clinical trials for mitochondrial myopathy because I was too fit. >> body mass index 18-32 kg/m2 and demonstrated sedentary behavior All the authors declare a conflict of interest with Amazentis. Nestlé just signed a partnership agreement with them [1] to help them develop the product. I guess they are actively seeking the exercise in a pill product. If they make it, it would be one of the biggest blockbusters in the history of medicine. [1] http://pdf.amazentis.com/pdf/Nestl%C3%A9_Health_Science_&_Amazentis_Press_Release_April_2_2019.pdf http://pdf.amazentis.com/pdf/Nestl%C3%A9_Health_Science_&_Am...