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Have been chatting with a radiation oncologist about this. His response: "imaging appears to be the same as F18-FDG-based PET. Just a bit more convenient since
by hsavit1 7y ago
Have been chatting with a radiation oncologist about this. His response: "imaging appears to be the same as F18-FDG-based PET. Just a bit more convenient since the patient doesn't need a normal blood sugar. And prob 2-10x the price"
- lipman 7y agoSeems like in certain tumor types it's better than FDG - still looking into it myself. Is FAPI available in the US already?
- mbrundle 7y agoAt first glance, this new tracer seems to yield a lower normal tissue uptake, and the reduced background signal could make it easier to locate tumours. FDG gets taken up by several organs inc heart and brain, whereas this tracer doesn’t appear to do so to that extent.
- sllrp 7y agoThe great advantage of these tracers is that they target actual structures over-expressed in cancers, which means they show far higher specificity than something like FDG. That means they can be used to find micrometastases, and with a different radio-label also be applied for highly targeted radiation therapy. Source: I used to work in the Heidelberg lab that published this study.