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> Caffeine, for example, has a different elimination half-life based on your genetics. I don't really feel woken up by coffee, could that be related? Nothing h
by mkagenius 7y ago
> Caffeine, for example, has a different elimination half-life based on your genetics.
I don't really feel woken up by coffee, could that be related? Nothing helps more than being hydrated (after 8 hours of no water) and ample sleep time.
- tachyonbeam 7y agoAFAIK some people also have a different variant of the adenosine receptor that makes it so caffeine doesn't bind to it in the same way. I recall seeing a study about this pass by, you might be able to find it with some googling. There's also a question of tolerance of course. If you drink coffee every day, then after a while you build tolerance and the effect becomes much milder. In order to assess whether coffee is effective you would need to take a break for a week. I know that when I have no tolerance, a strong cup of coffee has a very strong effect, I feel an instant mood lift and become much more active, I want to spend energy.
- a_random_name 7y agoIt's also possible that your brain is impacted by caffeine differently. I have adhd and caffeine can make me feel sleepy sometimes.