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I’ve taken and still take quite a few psychoactive drugs and have clearly noticed a lack of quality control and potency in generic drugs. I wouldn’t say they a
by mruts 7y ago
I’ve taken and still take quite a few psychoactive drugs and have clearly noticed a lack of quality control and potency in generic drugs.
I wouldn’t say they are poison, but in my experience they often don’t work as well.
One of the best examples is amphetamines. Name brand Adderall and Dexedrine are significantly more potent than the generic alternatives I’ve tried. Maybe this has to do with the binders, or maybe there is less amphetamines in it, I don’t know.
As an anecdote, my dad works as a pharma regulator for the FDA and never takes generic medication. He’s told me that generics are inadequately regulated to ensure equivalency to the original.
- EdwardDiego 7y agoApologies if I don't take your drug taking anecdotes as any kind of fact. If you knew that they were generics beforehand, and had preconceived beliefs about generics, your subjective experience of their recreational aspects is severely flawed.
- dRaBoQ 7y agoThe book provides details with FDA reports, court and patient cases why these are not anecdotes...
- EdwardDiego 7y agoIn America, yeah? As in, your regulators might be shit, but other countries might be better. The FDA have hardly been covering themselves in glory.
- deleted 7y ago[deleted]
- mruts 7y agoI’m prescribed them and have been taking some form of anphetamine for over 10 years. If it matters, I remember discovering this because I ended up taking a lot more because I wasn’t feeling them. Only afterwards did I notice they weren’t namebrand.
- ghostbrainalpha 7y agoAnecdotes in general are useless but the Adderall example is not just a single person's anecdote. It's an extremely common experience that almost everyone who takes the medication deals with. Many of the patients are kids who don't really understand what the difference between generic or name brand pills even is, so its hard to attribute the difference to their beliefs. Many pediatric doctors try to start treatment with generics and then move to the name brand as an alternative to increasing dosage.
- stallmanite 7y agoJust another anecdote for the pile but I’ve had the same experience with generic Adderall being significantly less potent. After a decade+ on the generic my insurance company switched me to brand name and it was utterly shocking how different it was. I had previously belived that generics were literally identical and figured I was experiencing a placebo effect. To try to understand what was going on I recapped 7 generics and 7 brand name pills so that I couldn’t identify which was which and had my wife give me one at random each day for 14 days with her keeping track of which was given when. After 14 days I had 100% accuracy identifying the generic vs brand name. Not good.