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Yes we can. Calorie restriction is well known slowing biological aging process. Sources: https://en.wikipedia.org/wiki/Calorie_restriction https://en.wikipedia
by novaRom 7y ago
Yes we can. Calorie restriction is well known slowing biological aging process.
Sources: https://en.wikipedia.org/wiki/Calorie_restriction https://en.wikipedia.org/wiki/Calorie_restriction
- hannob 7y agoThe existing research on CR seems to indicate that the closer you get to human-like animals the lesser it works. It worked very well in small organisms, once you go to apes the results are much less clear: https://www.theverge.com/2017/1/17/14287708/caloric-restriction-diet-monkey-health-longevity https://www.theverge.com/2017/1/17/14287708/caloric-restrict...
- whatshisface 7y agoOne thing is for sure, the average Western diet has so many calories than most people could probably do with a little restriction. (Not even to do anything special, just to return to a healthy state.)
- agent008t 7y agoAt the same time, many young men in the West struggle to put on weight and are underweight.
- vostok 7y agoDo you have a link to any quantitative data? I'd love to see how this has changed over time.
- phito 7y agooh yeap, been struggling with this forever.
- coldtea 7y agoTry some bacon.
- asark 7y agoCostco pizzas are $10 and over 4000 calories, eat one of those a day and if you don't get fat then you probably have a tapeworm in you or something. Or you're Michael Phelps during training season. ... or me at 18. Damn I miss that metabolism.
- coldtea 7y agoOr just have 12 stacked pancakes for breakfast at iHop + all the trimmings every day.
- phito 7y agoI don't like bacon.
- SeanDav 7y agoCan't decide if this is sarcastic/tongue-in-cheek or serious. If serious - would love to see source(s) for that statistic....
- agent008t 7y agoSerious. Don't have the statistics, but look up "gomad" for "gallon of full fat milk a day" - it is a thing for a reason.
- coldtea 7y agoEverything is a "thing for a reason". The reason could be a tiny outlier minority. You used the term "many".
- tumahimikka 7y agoThis is one of the dumbest comments I've ever read online, and I read Youtube comments. Gomad is for people trying to gain muscle mass and bulk up, not for people who are under a healthy weight.
- Falling3 7y agoSure it's a thing for a reason... the reason is guys who are into body lifting that was an easy source of calories and protein. It has nothing to do with your narrative.
- 7y ago
- mcv 7y agoIn the West? Men? I'd love to see statistics for that. In general, being overweight is a far, far larger problem in the West, and being underweight is extremely rare outside of eating disorders like anorexia. There are people who are naturally skinny due to how their metabolism works, but they are rarely truly underweight.
- threeseed 7y agoDepends how define many. 34.8% of men between 20-39 are obese in the US: https://www.cdc.gov/nchs/data/databriefs/db288.pdf https://www.cdc.gov/nchs/data/databriefs/db288.pdf That's far more a concern than whether men need to bulk up or not. Which naturally happens as men age and their metabolism slows anyway.
- coldtea 7y agoFor a small number of "many". [...] according to 2010 data from the Centers for Disease Control and Prevention, these are the measurements of the average American man: Height: 5 feet 9 inches (69.3 inches) Weight: 195.5 pounds Waist circumference: 39.7 inches
- jobigoud 7y agoHeight: 1.76 m, Weight: 88.7 kg, Waist circumference: 100.8 cm.
- TeMPOraL 7y agoDepends on the country, I suppose. I'm having a hard time finding stats for US that compare underweight and overweight % of population in one study. Anecdotal evidence from Europe: in our industry, culturally associated with obesity, I meet roughly equal amount of obese and underweight people. And I seriously doubt those underweight people spend time in the gym.
- cfj 7y agoThe second paragraph on that page: > In humans, the long-term health effects of moderate caloric restriction with sufficient nutrients are unknown.
- ekianjo 7y agoIt's not because it's unknown we should assume there is no effect (positive or negative). Rather, it's worth exploring.
- Kirth 7y agoIt's not because it's unknown we should assume this effect scales linearly, either..
- garmaine 7y agoAgree with the sentiment. But in this instance the data, preliminary as it is, is pointing towards "no effect" in humans. This is true of both animal studies, and preliminary statistical data on the few humans that have been trying CR for a few decades now. There is health improvement, but that's because CR is watching your diet, which is generally good for you. You correct for those factors and the effect basically disappears, at least into the high level of noise that comes with low sample sizes. But if you still believe in CR, even easier is taking resveratrol. My understanding is that the caloric restriction basically causes the production of resveratrol which is the cause of the beneficial effects in mice. So take resveratrol and eat a normal amount of healthy food should have the same result.
- goatlover 7y agoBut is it worth it to spend your youth restricting your calories enough to slow your aging a little bit?
- SlipperySlope 7y agoYes it is. Been doing it for decades and the difference between me and 4 brothers is obvious.
- qwsxyh 7y agoI swear most HN users have some form of orthorexia.
- malvosenior 7y agoI had never heard of that term but now that I know what it is, I think you’re right. There are so many very strong opinions about diet here and very little quality data to back it up (because for the most part it doesn’t exist).
- maxerickson 7y agoEat the shark before it eats you.
- mlrtime 7y ago"There are so many very strong opinions about diet" This is true for almost every group including scientists studying nutrition, it changes frequently.
- francisofascii 7y agoDiet and the human body in general is a complex system the HN users want to understand, hack, optimize, perfect.
- qwsxyh 7y agoThe last person I would trust to "hack" or "optimise" the human body is an orange website user.
- coldtea 7y agoOr they just go with the defaults for their social circles and salary brackets... (Which includes people into Goop and such -- hardly the "hackers" that want to analyze and hack the human body).
- sametmax 7y agoGive something to hack to geeks...
- deytempo 7y agoThis has to do with mitochondrial metabolic processes being the most efficient to break down smaller quantities of sugar. There are mitochondrial mechanisms to break down a lot at once that are turned on in the presence of more sugar but they just aren’t as finely tuned and thus generate free radicals which can cause cellular problems. There really wasn’t a point throughout evolutionary history where there was a prolonged abundance of sugar available to the degree it is today. Because of that, the mechanisms to break down a lot of carbohydrates/sugars at the same time just did not evolve to be as operationally efficient. Free radicals can cause DNA/RNA disruptions and also damage other processes. Source: father is a dedicated microbiologist
- GarrisonPrime 7y agoInteresting to know about free radical creation when mitochondria are overwhelmed. I’m sure there’s a lot more factors involved in aging however, not the least of which would be senescent cells. Telomeres only allow cells to divide ~50 times before they’re unable to replicate further.
- have_faith 7y agoUnable or won't?
- anticensor 7y agoBefore they start eating their own instructions. Every chromosome will become a Y chromosome some time in the future if we do not invent the necessary means.
- Madmallard 7y agoAsk your father about drug induced mitochondrial dysfunction. I had ciprofloxacin 4 years ago and my exercise tolerance swiftly dropped in the months afterward. Research tells me this is due to mtdna depletion and dna damage and I just want to know how to get better. I now have stage 1 diastolic dysfunction and a plethora of seemingly unrelated problems, coming from none before.
- ohaideredevs 7y ago>Calorie restriction is well known slowing biological aging process Cut calories and you cut the amount of cardio and strength training you can do. This cuts muscles mass, bone density, and takes away the IQ-increasing brain simulation factors away. I am not sold at all.
- AstralStorm 7y agoDo you now? Is there any actual study on this after the few weeks of adaptation or even at target reduced weight?