I've been a happy QFMLWY user for many years. It greatly eased my wrist pain and I feel a lot more efficient at typing. It took me about a month to switch from

I've been a happy QFMLWY user for many years. It greatly eased my wrist pain and I feel a lot more efficient at typing. It took me about a month to switch from QWERTY, going cold turkey. I highly recommend it. The drawback is that I'm now not able to touch type on a QWERTY layout anymore. However, I think that's only because I no longer need that skill. I presume that if I had to type on QWERTY regularly, I'd be able to touch type on both layouts.