The largest cause of disease progression in HIV is adherence between 70 and 90 percent. Hypertension, Diabetes, etc. All these long term problems have adheren

The largest cause of disease progression in HIV is adherence between 70 and 90 percent. Hypertension, Diabetes, etc. All these long term problems have adherence rates less then 70%. Resistance is low on the list for reasons for nonadherence. More common reasons include forgetting (because human brains are lousy alarm clocks), not getting refills, not renewing the rx, and not being able to afford it. One problem that happens is people fail to take meds as prescribed, get sicker, go back to the doctor, get a higher dose, take it right, and take too much since the doctor was operating under the assumption that the previous dose was taken. This is responsible for about 10% of hospital and 24% of nursing home admittances, at a cost of 100 billion. There are many 2007 and 2008 medical journal articles about how this is a huge problem desperate for a solution. Its not that people don't want to take the med, in most cases. Its that it takes more then wanting to adhere to make it happen, and the medical industry has no good solution.