> We need to end off label use. Saying a drug is approved for one diagnosis and then allowing it for any other diagnosis is, in the modern age, simply crazy. On

> We need to end off label use. Saying a drug is approved for one diagnosis and then allowing it for any other diagnosis is, in the modern age, simply crazy. One might as well not have fda approval. Everyday in England 30,000 people with learning disability take a psychotropic medication when they don't have the condition that the medication is licensed for. NHS England has a programme to stop this misuse of medication. It's called STOMP - STop Over Medicating People with LD. https://www.england.nhs.uk/learning-disabilities/improving-health/stomp/ https://www.england.nhs.uk/learning-disabilities/improving-h... This medication is often off-label use of anti-psychotic medication, used for a "sedative" effect. People with learning disability are at increased risk of constipation (sensory issues around food; reduced range of food being eaten; not much say about what they eat; reduced access to exercise; etc etc), and these meds often have constipation as a side effect. This combination causes harm. It sometimes kills people. There's variable awareness of constipation as a side effect of clozapine. Most doctors know about agranularcytosis, and they're aware constipation can be a problem. But there are some doctors who don't know that the constipation side effect kills more people than agranularcytosis. I agree. It's really important to stop misuse of medication.