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I have to disagree. Whole genome sequencing has only been prevalent in the past few years. I can agree that much of this has to do with the cost and complexity
by dkoston 7y ago
I have to disagree. Whole genome sequencing has only been prevalent in the past few years. I can agree that much of this has to do with the cost and complexity involved and the rise of new techniques and more computing power has opened up whole genome sequencing which has only been around since 2003 (1) and has been highly expensive and not used frequently until recently (2).
The majority of research I’ve come across in the past decade has been still focusing on DNA microarrays and qPCR which are focused on coding DNA. Perhaps I’m not seeing all the papers published for the studies you are familiar with and as such have a bias to believe that only a small portion of research is using NGS and is focused on non coding DNA.
1 https://www.yourgenome.org/facts/timeline-history-of-genomics https://www.yourgenome.org/facts/timeline-history-of-genomic...
2 https://academic.oup.com/hmg/article/25/R2/R157/2198171 https://academic.oup.com/hmg/article/25/R2/R157/2198171
- klmr 7y agoWell my own research has focused completely on noncoding DNA. So yes. It exists.