5-HT3 antagonism. https://en.wikipedia.org/wiki/Ondansetron https://en.wikipedia.org/wiki/Ondansetron Usually nausea is caused by the perception that your bod

5-HT3 antagonism. https://en.wikipedia.org/wiki/Ondansetron https://en.wikipedia.org/wiki/Ondansetron Usually nausea is caused by the perception that your body "doesn't feel right." Serotonin is responsible for the feeling of wellbeing. Just so happens that subreceptor 3 is more about well being feeling of the body :-)