Bonus: If you write plain, valid HTML your site will just work across all mainstream browsers and it will probably work reasonably wrt accessibility as well, -

Bonus: If you write plain, valid HTML your site will just work across all mainstream browsers and it will probably work reasonably wrt accessibility as well, -out of the box. It will also be reasonbly fast. You might be able to eke out more performance from a site that has a lot of interaction but I'd not take that for granted.