The smoking parallel isn't very illuminating. Eating food is necessary for survival; smoking tobacco isn't. And we've been eating cholesterol-containing anima

The smoking parallel isn't very illuminating. Eating food is necessary for survival; smoking tobacco isn't. And we've been eating cholesterol-containing animal products for many tens of millions of years, long before we became Homo sapiens, whereas the smoking of tobacco is a very recent phenomenon, way too recent to have any effect on evolutionary time scales. In what way has evolution optimized for smoking? It gives us cancer and kills us. We're clearly not optimized for it.