3 ms·
I love this warning about halfway down the page: "How Not to Use this Dataset As the images in RxRx1 are generated by carrying out biological experiments usin
by onychomys 7y ago
I love this warning about halfway down the page:
"How Not to Use this Dataset
As the images in RxRx1 are generated by carrying out biological experiments using reagents known as siRNAs, which are designed to target and knockdown a specific gene (more on this in another section), some may be tempted to use this to identify gene-specific morphological changes. DO NOT DO THIS. siRNAs are known to have significant off-target effects which you only have the chance to overcome through a number of computational methods and using multiple siRNAs per gene. As this dataset only includes one siRNA per gene for a random subset of genes, do not attempt to identify gene-specific signal. There are many ways you can convince yourself you have succeeded in this. You will be wrong. The data provided is insufficient for that task, and should thus be used to conduct research focused on alternative problems only. Just for clarity because we know somebody will ignore the warnings above, we’ll state it again more clearly: DO NOT USE THIS DATASET TO TRY TO GET AT GENE-SPECIFIC CHANGES. IT WILL NOT WORK."