3 ms·

So what they measure and where is the paper? I read the linked pr but find nothing about them

• ufo 7y ago
  I don't understand the details but here is the link to the paper https://www.pnas.org/content/early/2019/04/24/1901274116 https://www.pnas.org/content/early/2019/04/24/1901274116
  • leemailll 7y ago
    Thanks for the link. I read the paper and it seems that they just measure the impedance (or resistance) of the cell membrane with an artificial increase of NaCl in the extracellular environment (ie plasma in the text). The final NaCl concentration looks like to be doubled than the normal range. This might be an intersting finding, but I can't figure out why the impdecance of membrane need to be measured with increased NaCl in the plama. And whether it is only related with Na+ or Cl- change.
    • ufo 7y ago
      The salty plasma removes water from inside the cells by osmosis. The authors say that this technique is a common model for studying cellular response to stress.
      • leemailll 7y ago
        The thing is if they just want to create a hyperosmotic solution they can add something won't be transported across the membrane, the way they did will change a lot of things on the membrane and inside the cell rather than stress introduced by hyperosmotic stress