I was interested in the cause of the "toxicity" which resulted in at least one death as a result of the CAR-T treatment - the article links to: https://www.natu

I was interested in the cause of the "toxicity" which resulted in at least one death as a result of the CAR-T treatment - the article links to: https://www.nature.com/news/safety-concerns-blight-promising-cancer-therapy-1.20763 https://www.nature.com/news/safety-concerns-blight-promising... My take was its hard to find proteins unique to the cancerous target that isnt also present in healthy tissue. It even mentions a patient being treated where the target proteins where also present at lower levels in the patients brain. So I guess the programmed T-cells run amuck typically in the course of treatment. I hope that intense competition to control the most effective new cancer treatments accelerates development. This is once the treatments become mainstrain, not really addressing the article.