My biochemistry education is 20 years old.. As you say DNA encodes the sequence of amino acids. Protein folding is a thermodynamic problem as parts of the prote

My biochemistry education is 20 years old.. As you say DNA encodes the sequence of amino acids. Protein folding is a thermodynamic problem as parts of the protein stick to other parts and bonds try to achieve a low energy shape. There are enzymes, co-enzymes, and other molecules that can help a protein to achieve its proper shape.