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This reminds me of the current omnigenic hypothesis about genes. That unexpectedly almost every gene seems to affect the expression of traits. https://www.qua
by JohnJamesRambo 8y ago
This reminds me of the current omnigenic hypothesis about genes. That unexpectedly almost every gene seems to affect the expression of traits.
https://www.quantamagazine.org/omnigenic-model-suggests-that-all-genes-affect-every-complex-trait-20180620/ https://www.quantamagazine.org/omnigenic-model-suggests-that...
"Drawing on GWAS analyses of three diseases, they concluded that in the cell types that are relevant to a disease, it appears that not 15, not 100, but essentially all genes contribute to the condition. The authors suggested that for some traits, “multiple” loci could mean more than 100,000."
- nonbel 8y agoThat is just a special case of the "everything is correlated" principle.